1) Cat. No.: TRC-A794710; 2) Chemical Name: Avosentan; 3) CAS No.: 290815-26-8; 4) Mol. Formula: C23H21N5O5S; 5) Mol. Weight: 479.51; 6) Packing Size: 10mg / 100mg; 7) Appearence: ; 8) Application Notes: Avosentan is a competitive antagonist of Endothelin-1 (ET-1) with a high selectivity for the ETA receptor. Avosentan may be a potential option in the treatment of glaucoma.; 9) Synonym: N-[6-Methoxy-5-(2-methoxyphenoxy)-2-(4-pyridinyl)-4-pyrimidinyl]-5-methyl-2-pyridinesulfonamide; Ro 67-0565; SPP 301;; 10) Solubility: ; 11) Storage condition: ; 12) References: Dieterle, W. et al.: J. Clin. Pharmacol., 44, 59 (2004); Dieterle, W. et al.: Int. J. Clin. Pharmacol. Ther., 43, 178 (2005); Wang, R.-F. et al.: Curr. Eye Res., 36, 41 (2011);